Prof. Yaron Orenstein

 

ABOUT MY WORK

 

Computational modeling of protein-DNA and -RNA binding

Our research focuses on computational modeling of protein-DNA and -RNA interactions. Protein-DNA and -RNA interactions are key regulators of gene expression, and as such are involved in almost any process in the cell, including many diseases. Technologies measuring these interactions produce thousands and millions of data points in a single experiment, which can only be analyzed computationally.

In our research, we develop efficient computational methods to analyze the data and produce accurate models to predict new interactions and better understand the process at test. To handle the vast amounts of data, I develop efficient methods to process the data and extract relevant information on which I apply learning methods to infer accurate predictive models.

For more information, please visit our lab in the following link: lab